Hiszpan, Francesco Ventoso (Carmiooro – NGC) wygrał klasyk 1.HC UCI – Paris-Bruxelles. Drugie miejsce zajął Francuz, Romain Feillu (Vacansoleil). Trzeci był doświadczony Stefan Van Dijck (Verandas Willems).
Zawodnicy rywalizowali na 218.5km trasie z Soissons do Bruxelles. Od samego początku dochodziło do wielu akcji zaczepnych. Jednak żadna z nich się nie powiodła. Bardzo dobrze współpracowały ekipy sprinterów, którzy od wielu lat walczą o zwycięstwo w klasyku. W tym roku sojusz zawarły ekipy Vacansoleil, Katusha oraz Skil-Shimano.
W finałowym sprincie zagubił się jeden z faworytów, Robbie McEwen (Katusha). Australijczyk zajął dopiero 25. miejsce. Wykorzystał to doświadczony Ventoso, który pokonał byłego lidera wyścigu Tour de France, Romaina Feillu oraz Stefana Van Dijcka.
Pełne wyniki Paryż – Bruksela 2010:
| 1 | Francesco Ventoso Alberdi (Spa) Carmiooro – NGC | 4:59:00 | |
| 2 | Romain Feillu (Fra) Vacansoleil Pro CT | ||
| 3 | Stefan Van Dijck (Ned) Verandas Willems | ||
| 4 | Paul Martens (Ger) Rabobank | ||
| 5 | Jens Keukeleire (Bel) Cofidis Le Credit en Linge | ||
| 6 | Enrico Rossi (Ita) Ceramiche Flaminia-Bossini Doccé | ||
| 7 | Tom Veelers (Ned) Skil – Shimano | ||
| 8 | Roy Curvers (Ned) Skil – Shimano | ||
| 9 | Alexander Kristoff (Nor) BMC Racing Team | ||
| 10 | Edwig Cammaerts (Bel) Lotto Bodysol | ||
| 11 | Gabriel Rasch (Nor) Cervélo Test Team | ||
| 12 | Gregory Rast (Swi) Team Radioshack | ||
| 13 | Gorik Gardeyn (Bel) Vacansoleil Pro CT | ||
| 14 | Kevyn Ista (Bel) Cofidis Le Credit en Linge | ||
| 15 | Maxime Vantomme (Bel) Team Katusha | ||
| 16 | Franck Bouyer (Fra) BBox Bouygues Telecom | ||
| 17 | Klaas Lodewyck (Bel) Topsportvlaanderen Mercator | ||
| 18 | Fabrice Piemontesi (Ita) Androni Giocattoli | ||
| 19 | Jimmy Casper (Fra) Saur – Sojasun | ||
| 20 | Aristide Ratti (Ita) Carmiooro – NGC | ||
| 21 | Jens Debusschere (Bel) Omega Pharma-Lotto | ||
| 22 | Gilles Devillers (Bel) Lotto Bodysol | ||
| 23 | Jerome Baugnies (Bel) Topsportvlaanderen Mercator | ||
| 24 | Preben Van Hecke (Bel) Topsportvlaanderen Mercator | ||
| 25 | Robbie McEwen (Aus) Team Katusha | ||
| 26 | Egidijus Juodvalkis (Ltu) Palmans – Cras | ||
| 27 | Bert De Backer (Ned) Skil – Shimano | ||
| 28 | Gregory Habeaux (Bel) Verandas Willems | ||
| 29 | Koos Moerenhout (Ned) Rabobank | ||
| 30 | Addy Engels (Ned) Quick Step | ||
| 31 | Diego Tamayo Martinez (Col) Carmiooro – NGC | ||
| 32 | Johan Coenen (Bel) Topsportvlaanderen Mercator | ||
| 33 | Reinier Honig (Ned) Acqua & Sapone- D’Angelo & Anteri | ||
| 34 | David Boucher FRE19800317 Landbouwkrediet | ||
| 35 | Thomas Vedel Kvist (Den) Quick Step | ||
| 36 | Andy Cappelle (Bel) Verandas Willems | ||
| 37 | Andreas Klier (Ger) Cervélo Test Team | ||
| 38 | Gerben Löwik (Ned) Omega Pharma-Lotto | ||
| 39 | Wim De Vocht (Bel) Team Milram | ||
| 40 | Luca Solari (Ita) Androni Giocattoli | ||
| 41 | Yuriy Trofimov (Rus) BBox Bouygues Telecom | ||
| 42 | Kevin Reza (Fra) BBox Bouygues Telecom | ||
| 43 | Jetse Bol (Ned) Rabobank | ||
| 44 | Giovanni Visconti (Ita) ISD – Neri | ||
| 45 | Jurgen Roelandts (Bel) Omega Pharma-Lotto | 0:00:15 | |
| 46 | Volodymir Gustov (Ukr) Cervélo Test Team | ||
| 47 | Yannick Talabardon (Fra) Saur – Sojasun | ||
| 48 | Luca Paolini (Ita) Acqua & Sapone- D’Angelo & Anteri | ||
| 49 | Michael Schar (Swi) BMC Racing Team | ||
| 50 | Alessandro Maserati (Ita) Ceramiche Flaminia-Bossini Doccé | 0:00:18 | |
| 51 | Kenny Dehaes (Bel) Omega Pharma-Lotto | 0:00:22 | |
| 52 | Alessandro Donati (Ita) Acqua & Sapone- D’Angelo & Anteri | ||
| 53 | Rafaâ Chtioui (Tun) Acqua & Sapone- D’Angelo & Anteri | 0:00:25 | |
| 54 | Bert Scheirlinckx (Bel) Landbouwkrediet | 0:00:29 | |
| 55 | Frederic Amorison (Bel) Landbouwkrediet | ||
| 56 | Damiano Margutti (Ita) Androni Giocattoli | ||
| 57 | Mario Aerts (Bel) Omega Pharma-Lotto | ||
| 58 | Denys Kostyuk (Ukr) ISD – Neri | ||
| 59 | Koen Barbe (Bel) Landbouwkrediet | ||
| 60 | Edoardo Girardi (Ita) Ceramiche Flaminia-Bossini Doccé | ||
| 61 | Kenny Terweduwen (Bel) Jong Vlaanderen – Bauknecht | ||
| 62 | Thomas Rohregger (Aut) Team Milram | ||
| 63 | Rubens Bertogliati (Swi) Androni Giocattoli | ||
| 64 | Massimo Codol (Ita) Acqua & Sapone- D’Angelo & Anteri | ||
| 65 | Dominique Cornu (Bel) Skil – Shimano | 0:00:35 | |
| 66 | Andrea Tonti (Ita) Carmiooro – NGC | 0:00:37 | |
| 67 | Vladimir Miholjevic (Cro) Acqua & Sapone- D’Angelo & Anteri | ||
| 68 | Francesco Failli (Ita) Acqua & Sapone- D’Angelo & Anteri | ||
| 69 | Pavel Brutt (Rus) Team Katusha | ||
| 70 | Stijn Devolder (Bel) Quick Step | ||
| 71 | Bjorn Leukemans (Bel) Vacansoleil Pro CT | 0:00:42 | |
| 72 | Alberto Ongarato (Ita) Vacansoleil Pro CT | 0:00:45 | |
| 73 | Ricardo Ricco (Ita) Vacansoleil Pro CT | 0:00:47 | |
| 74 | Maarten Wynants (Bel) Quick Step | ||
| 75 | Cristiano Fumagalli (Ita) Ceramiche Flaminia-Bossini Doccé | ||
| 76 | Bauke Mollema (Ned) Rabobank | 0:00:55 | |
| 77 | Sep Vanmarcke (Bel) Topsportvlaanderen Mercator | 0:01:11 | |
| 78 | Marco Marcato (Ita) Vacansoleil Pro CT | 0:01:25 | |
| 79 | Joeri Calleeuw (Bel) Jong Vlaanderen – Bauknecht | 0:01:27 | |
| 80 | Simon Geschke (Ger) Skil – Shimano | ||
| 81 | Jos Van Emden (Ned) Rabobank | 0:02:31 | |
| 82 | Adam Blyth (GBr) Omega Pharma-Lotto | ||
| 83 | Fabrice Jeandesboz (Fra) Saur – Sojasun | 0:02:44 | |
| 84 | Yukihiro Doi JAP19830918 Skil – Shimano | 0:03:02 | |
| 85 | Gert Steegmans (Bel) Team Radioshack | 0:03:06 | |
| 86 | Dieter Capelle (Bel) Verandas Willems | 0:03:37 | |
| 87 | Lars Boom (Ned) Rabobank | ||
| 88 | Sjef De Wilde (Bel) Verandas Willems | ||
| 89 | Artem Ovechkin (Rus) Team Katusha | ||
| 90 | Stijn Vandenbergh (Bel) Team Katusha | ||
| 91 | Alessandro De Marchi (Ita) Androni Giocattoli | ||
| 92 | Quentin Bertholet (Bel) Lotto Bodysol | 0:04:07 | |
| 93 | Rudy Rouet (Bel) Lotto Bodysol | 0:05:51 | |
| 94 | Enrico Peruffo (Ita) Carmiooro – NGC | ||
| 95 | Clinton Avery (NZl) Team Radioshack | ||
| 96 | Benjamin Verraes (Bel) Jong Vlaanderen – Bauknecht | ||
| 97 | Martin Kohler (Swi) BMC Racing Team | ||
| 98 | Florian Stalder (Swi) BMC Racing Team | ||
| 99 | Kurt Hovelijnck (Bel) Quick Step | ||
| 100 | Marco Velo (Ita) Quick Step | ||
| 101 | Thomas De Gendt (Bel) Topsportvlaanderen Mercator | ||
| 102 | Tim Mertens (Bel) Topsportvlaanderen Mercator | ||
| 103 | Tom Van den Haute (Bel) Landbouwkrediet | ||
| 104 | Luis Mate Mardones (Spa) Androni Giocattoli | ||
| 105 | Tom Vanbecelaere (Bel) Palmans – Cras | ||
| 106 | Christophe Premont (Bel) Lotto Bodysol | ||
| 107 | Romain Matheou (Fra) Saur – Sojasun | ||
| 108 | Jonas Vangenechten (Bel) Verandas Willems | ||
| 109 | Cadel Evans (Aus) BMC Racing Team | ||
| 110 | Cameron Wurf (Aus) Androni Giocattoli | ||
| 111 | Simon Zahner (Swi) BMC Racing Team | ||
| 112 | Robin Chaigneau (Ned) Skil – Shimano | ||
| 113 | Fumiyuki Beppu (Jpn) Team Radioshack | ||
| 114 | James Vanlandschoot (Bel) Verandas Willems | ||
| 115 | Joeri Stallaert (Bel) Jong Vlaanderen – Bauknecht | ||
| 116 | Wilfried Cretskens (Bel) Omega Pharma-Lotto | ||
| 117 | Oleksandr Kvachuk (Ukr) ISD – Neri | ||
| 118 | Dmytriy Krivtsov (Ukr) ISD – Neri | ||
| 119 | Cyril Lemoine (Fra) Saur – Sojasun | ||
| 120 | Nicolas Edet (Fra) Cofidis Le Credit en Linge | ||
| 121 | Frederique Robert (Bel) Quick Step | ||
| 122 | Stéphane Auge (Fra) Cofidis Le Credit en Linge | ||
| 123 | Yoann Bagot (Fra) Cofidis Le Credit en Linge | ||
| 124 | Alexander Wetterhall (Swe) Cervélo Test Team | ||
| 125 | Floris Goesinnen (Ned) Skil – Shimano | ||
| 126 | Jens Mouris (Ned) Vacansoleil Pro CT | ||
| 127 | Guillaume Le Floch (Fra) BBox Bouygues Telecom | ||
| 128 | Sergey Ivanov (Rus) Team Katusha | ||
| 129 | Sergey Klimov (Rus) Team Katusha | ||
| 130 | Giovanni Bernaudeau (Fra) BBox Bouygues Telecom | ||
| 131 | Filippo Baggio (Ita) Ceramiche Flaminia-Bossini Doccé | ||
| 132 | Diego Caccia (Ita) ISD – Neri | ||
| 133 | Tony Hurel (Fra) BBox Bouygues Telecom | ||
| 134 | Paolo Longho Borghini (Ita) ISD – Neri | ||
| 135 | Kalle Kriit (Est) Cofidis Le Credit en Linge | ||
| 136 | Matthias Russ (Ger) Team Milram | ||
| 137 | Tom Stubbe (Bel) Omega Pharma-Lotto | ||
| 138 | Sven Vandousselaere (Bel) Jong Vlaanderen – Bauknecht | ||
| 139 | Dimitri Muravyev (Kaz) Team Radioshack | ||
| 140 | Sebastien Joly (Fra) Saur – Sojasun | ||
| 141 | Kevin Van Impe (Bel) Quick Step | ||
| 142 | Steven Caethoven (Bel) Landbouwkrediet | ||
| 143 | Benjamin Gourgue (Bel) Landbouwkrediet | ||
| 144 | Geert Omloop (Bel) Palmans – Cras | ||
| 145 | Andrea Piechele (Ita) Carmiooro – NGC | ||
| 146 | Eric Berthou (Fra) Carmiooro – NGC | ||
| 147 | Rob Goris (Bel) Palmans – Cras | 0:09:28 | |
| 148 | Jonathan De Witte (Bel) Lotto Bodysol | ||
| 149 | Jeremy Burton (Bel) Lotto Bodysol | ||
| 150 | Jure Kocjan (Slo) Carmiooro – NGC | ||
| 151 | Joaquin Novoa Méndez (Spa) Cervélo Test Team | ||
| 152 | Joao Correia (Por) Cervélo Test Team | ||
| 153 | Danilo Napolitano (Ita) Team Katusha | ||
| 154 | Steven De Neef (Bel) Jong Vlaanderen – Bauknecht | ||
| 155 | Stéphane Poulhies (Fra) Saur – Sojasun | ||
| 156 | Damien Gaudin (Fra) BBox Bouygues Telecom | ||
| 157 | Rick Flens (Ned) Rabobank | ||
| 158 | Liewe Westra (Ned) Vacansoleil Pro CT | ||
| 159 | Daryl Impey (RSA) Team Radioshack | ||
| 160 | Danielle Colli (Ita) Ceramiche Flaminia-Bossini Doccé | 0:10:08 | |
| 161 | Sven Van den Houte (Bel) Verandas Willems | ||
| 162 | Roger Kluge (Ger) Team Milram | ||
| 163 | Jimmy Engoulvent (Fra) Saur – Sojasun | 0:11:51 | |
| 164 | Ben Hermans (Bel) Team Radioshack | 0:12:29 | |
| 165 | Cole House (USA) BMC Racing Team | ||
| 166 | Artur Gajek (Ger) Team Milram | ||
| 167 | Timothy Vangheel Bel19860826 Palmans – Cras | 0:13:24 | |
| 168 | Sebastien Delfosse (Bel) Landbouwkrediet | 0:15:00 | |
| 169 | Alberto Loddo (Ita) Androni Giocattoli | 0:16:31 | |
| 170 | Wim Stroetinga (Ned) Team Milram | ||
| 171 | Simone Masciarelli (Ita) Acqua & Sapone- D’Angelo & Anteri | ||
| 172 | Aidis Kruopis (Ltu) Palmans – Cras | ||
| 173 | Jean Eudes Demaret (Fra) Cofidis Le Credit en Linge | ||
| 174 | Ivan Rouny (Rus) Team Radioshack | ||
| 175 | Jean Zen (Fra) Palmans – Cras | ||
| 176 | Oscar Gatto (Ita) ISD – Neri |
